Endocrine Abstracts

Introduction: It is suggested that hyperuricemia in type 2 diabetes (T2DM) patients causes reactive oxygen species (ROS) accumulation, which causes the destruction of beta cells of the pancreas and contributes to T2DM. This study aimed to analyze the relationship between vitamin D deficiency (which is reciprocally related to Serum Uric Acid (SUA) levels), hyperuricemia, and levels of ROS scavengers in T2DM patients, and to investigate the effect of vitamin D supplementation on...

Purpose: Type two diabetes mellitus (T2DM) is a chronic disease of debilitating complications. Good glycemic control could delay disease progression and microvascular complications. Nonetheless, some patients cannot maintain glycemic control.Patients and Methods: We recruited 340 T2DM patients on metformin therapy and categorized them according to their HbA1c levels into patients with good vs poor glycemic control. The levels of serum leptin were measure...